The alpha300 R represents a new generation of Raman imaging systems, focusing on high resolution as well as high speed spectrum and image acquisition. Its sensitive setup allows for the nondestructive imaging of chemical properties without specialized sample preparation. In typical experiments, the acquisition time for a single Raman spectrum can be as low as 0.76 milliseconds. This results in complete images consisting of tens of thousands of spectra being collected within a few minutes. Differences in chemical composition, although completely invisible in the optical image, will be apparent in the Raman image and can be analyzed with a resolution down to 200 nm. The confocal setup reduces unwanted background signals, enhances contrast and provides depth information.