Culturing of adherent cells/tissues in a sterile natural 3-D environment continuously for over 12 months allows for impressive cell densities exceeding 10^10 all in a compact laboratory tabletop apparatus. This massive concentration of cells (up to 10,000x more than conventional systems) in the Glen Mills / Zellwerk Z®RP Reactor System opens new areas for development in medicine, classic cell and stem cell research, tissue growth for replacements, large-scale biochemical production by perfusion, and others. Equipment complies with GLP, GCP, GTP, and GMP standards.
Download equipment bulletin in PDF format here or visit the manufacturer's web site - Zellwerk GmbH.
Equipment outline - Employing turning shaft technology Z®RP overcomes failings of rotation bottles, t-flasks, fluidized beds, and other methods. The growing cells, immobilized on the ceramic support, are rotated through the air and then dipped into the medium. This motion allows for the optimal controlled perfusion of nutrients and metabolic products without shear stress. The typical system consists of two essential components: the Breeder Package and the Scaffold.